There's a juicy South Lincolnshire derby at Spalding United on Saturday when lower level Deeping Rangers are the visitors.
The winners then have another cracking local contest away to Stamford AFC in the preliminary round.
Deeping have had a stuttering start to their United Counties Premier Division season as they followed a 2-1 defeat at Sherwood Colliery on opening day with a 1-1 home draw against Boston Town on Tuesday.
Thomas Smith scored against Boston with Keelan Walker grabbing a late consolation at Sherwood.
Darren Ferguson says Peterborough United lacked the ambition to stay in the Championship and he's staying patient while waiting for the right job opportunity to come along
Peterborough United linked with Ben Garrity as Port Vale boss seeks to play down link
Supercomputer predicts likely outcome for Plymouth Argyle v Peterborough United, Derby County v Barnsley, Sheffield Wednesday v Charlton Athletic, Bristol Rovers v Oxford United and every other League One fixture
Peterborough United should change their winning League One team!
Strong EFL Cup performance has given Peterborough United boss Grant McCann decisions to make ahead of Plymouth rematch
Spalding start their Northern Premier Midlands Division campaign on August 13.
Yaxley are at Ipswich Wanderers in the FA Cup on Saturday when Wisbech Town host Ely City, March Town host Sheringham and Pinchbeck United travel to Melton Town in extra preliminary round ties.
Holbeach United start their Thurlow Nunn Division One North season at home to Needham Market Under 23s on Saturday.