The air ambulance was called to the scene of a “very serious” crash involving a car and a lorry on the A605 this morning, Thursday May 11.
The road remains closed in both directions between the Elton turn, the B671 and the Warmington roundabout.
The crash took place at 10.20am and fire crews, police, ambulance and the air ambulance attended.
At least one person is said to have suffered serious injuries but details are still sketchy at this time.
A spokesman for the East of England Ambulance Service said: “We were called at 10.21am today to a report of a road traffic collision between a car and lorry on the A605 at Elton.
“A rapid response vehicle, ambulance crew, ambulance officer and Magpas air ambulance were dispatched.
“They are currently on scene treating two patients.”
Motorists are asked to find an alternative route.