Both lanes of the A1 southbound near Alwalton were shut this afternoon (Thursday, August 10) after a crash involving two lorries.
The collision occurred between a car transporter and a lorry carrying thousands of empty glass bottles.
One of the vehicles has a ruptured fuel tank, and fuel, along with thousands of bottles, are now strewn across the road.
The road was blocked at Alwalton with glass on both carriageways. One lane of the southbound side has now reopened and northbound is clear.
The A47 entry slip road is also closed.
An eyewitness said the cars on the transporter have also been badly damaged.
He said: “It’s wrecked the cars on the car transporter and spilt thousands and thousands of bottles onto the carriageway, which have smashed.
“It’s absolute carnage, it’s going to take hours to clear up.”
Traffic is queuing back to Stamford.