There were delays of over an hour on the A1 between Peterborough and Stamford this afternoon, Thursday.
Motorists faced delays for around six hours as the southbound carriageway was closed or partially following a crash between two lorries.
The crash involved between a car transporter and a lorry carrying thousands of empty glass bottles.
One of the vehicles had a ruptured fuel tank, and fuel, along with thousands of bottles, are now strewn across the road.
The road was blocked at Alwalton with glass on both carriageways. The road was fully reopened at 8.38pm.
An eyewitness said the cars on the transporter had also been badly damaged.
He said: “It’s wrecked the cars on the car transporter and spilt thousands and thousands of bottles onto the carriageway, which have smashed.
“It’s absolute carnage, it’s going to take hours to clear up.”
Traffic queued back to Stamford with Highways England reporting delays of an hour.