The A47 was closed in both direction between Peterborough and Wisbech after a four collision.
Three cars and a van collided in Guyhirn this morning. Police were called to the incident at 8.30am.
Police were on the scene and recovery took place to get traffic moving again.
There have been no reports of injuries, a police spokeswoman said.
The road had reopened around 11.20am.