There are delays on the westbound carriageway of the Nene Parkway at Hampton after a car rolled onto its roof.
The accident happened at about 4.30pm at the junction of the Nene Parkway and the Fletton Parkway.
A Mitsubishi 4x4 car was involved in the crash. A Cambridgeshire police spokesman said the driver had not been seriously hurt in the crash.
Recovery teams are on the way to the incident, delays are expected throughout the evening rush hour.