Cambridgeshire seek their first win in any competition this season when hosting Hertfordshire at Saffron Walden in the Minor Counties Championship (June 19-21).
Cambs lost three of their four one-day games in the Unicorns Trophy (the other was abandoned) and drew their opening Championship match with Norfolk after a final day washout.
Captain Lewis Bruce will be joined by Peterborough Town clubmates Asim Butt, David Sayer and Joe Dawborn, while Wisbech pair Sam Rippington and Josh Bowers have also been selected.
Nassington slow bowler Harrison Craig, who made a promising debut at the age of 16 against Norfolk last time out, has been left out.
Cambs: N. Jeyeratnum, P. Richer, B. Smith, B. Bryant, L. Bruce, A. Butt, D. Sayer, J. Bowers, S. Rippington, J. Dawborn, J. Arksey.